- 中文核心期刊
- 中国科技核心期刊
- CSCD
- ISSN 1007-6336
- CN 21-1168/X
| Citation: |
JIN Wei, YAO Jing-yuan, JIA Bao-lin, LIANG Yu-bo, LV Song-hui. Extraction and purification of paralytic shellfish toxins GTX1/4 and GTX2/3[J]. Chinese Journal of MARINE ENVIRONMENTAL SCIENCE, 2021, 40(3): 425-429. DOI: 10.12111/j.mes.20190300
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GTX1/4 and GTX2/3 are the most harmful algal toxins in the coastal waters of China. The paralytic shellfish toxins from mussel samples were extracted with 0.18 mol/L formic acid aqueous solution, cleaned up with ethyl acetate and trichloromethane. Then, the crude PSTs solutions were separated by macroporous adsorption resin SP700 and purified by preparative high performance liquid chromatographic (PHPLC) coupled with Hillic column. It developed an effective method for the preparation of paralytic shellfish toxins reference materials.
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