Abstract: Species sensitivity analysis (SSD), widely accepted as an ecological toxicity assessment method in recent years, has also been employed for comprehending and deriving environmental safety thresholds for microplastics. Due to the absence of microplastic toxicity testing standards, coupled with the inherent diversity in the polymer type and the persistence of microplastics, accurate hazard assessment of microplastics remains challenging. Given these challenges, we suggest implementing a semi-quantitative approach to assess data quality and constructing sub-datasets. This will enhance the accuracy of SSD in predicting the environmental safety threshold for microplastic analysis. These recommendations lay the foundation for future assessments of microplastic ecological toxicity.