Abstract: Residual levels, composition profiles, bioaccumulation and risk assessment of Organochlorine pesticides and Polychlorinated biphenyls were determined in ten species of edible fish at Quanzhou bay in 2013.Concentrations of OCPs and PCBs ranged from 11.20×10^-9~74.51×10^-9 and 4.48×10^-9~20.44×10^-9 (wet weight), respectively.Different residual levels of OCPs and PCBs were determined in different fish species, exhibiting highest levels in Liza carinatus and konosirus punctatus.DDTs were the predominant components of OCPs, and the sources of OCPs were mainly derived from historical residue; and the high chlorinated PCBs were the predominant congeners of PCBs.The edible fishes in Quanzhou bay showed strong accumulation capacity to DDTs, and PCBs with less than seven chlorine atoms had higher bioaccumulation potentials with the increase of chlorine atom number, while PCBs with more than seven chlorine atoms were not considered bioaccumulative.The results of assessment showed that PCBs in edible fished from Quanzhou bay may endanger human health.Moreover, the daily dietary consumption of edible fishes and meals per month of Liza carinatus, konosirus punctatus, yellow croaker, Johnius, Argyrosomus and four barbudo were all lower than the safety threshold of 142.2 g/d and 16 meals/month, suggesting that consumers should not overeat these edible fishes.